National Center for Advancing Translational Sciences | Catalyzing Innovation
Volume 05 • Issue 02 • February 23, 2016

Director's Message

Director's photo

During the weeks leading up to the annual Rare Disease Day at NIH, I have been reflecting on my career path in clinical medicine and therapeutics development. Three decades ago, when I was training to be a neurologist...


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1536 well plates for flow cytometric analysis

CTSA Program Collaboration Provides Drug Discovery Expertise

Clinical and Translational Science Awards (CTSA) Program hub researchers at the University of New Mexico, University of Kansas Medical Center, and University of North Carolina, Chapel Hill, are collaborating to more rapidly test existing drugs and advance those showing promise into clinical trials. Read more >

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Assay Guidance Manual Cover

Updated Assay Guidance Manual Now Available

Assay Guidance Manual editors recently added four new chapters to benefit drug discovery scientists worldwide. Two chapters feature strategies to identify and avoid false positive compounds from small-molecule screens. The other chapters offer practical guidelines for pharmacokinetics assessments and describe viability and toxicity assays for 3-D spheroids and microtissues. Read more >

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NCATS plate washer

Tox21 Researchers Publish Analysis of 10,000 Potentially Toxic Chemicals

In the January 26 issue of Nature Communications, researchers from the Toxicology in the 21st Century (Tox21) program published their first comprehensive analysis from screening a library of more than 10,000 chemicals for toxicity in 30 different human cell–based assays (tests). Read more >

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NCATS staff at The Children’s Inn at NIH

NCATS Staff Serve Dinner to Children’s Inn Patients

In recognition of Rare Disease Day at NIH on February 29, NIH staff — including NCATS Director Christopher P. Austin, M.D.; Deputy Director Pamela McInnes, D.D.S., M.Sc.; Office of Rare Diseases Research Director Petra Kaufmann, M.D., M.Sc.; and NIH Clinical Center representatives ― served dinner to patients and their families at The Children’s Inn at NIH. Read more >

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Portraits of Drs. Gopal-Srivastava and Inglese

Meet More of NCATS’ Staff

Mary Purucker, M.D., Ph.D., is a medical officer in the NCATS Division of Clinical Innovation. Wenwei Huang, Ph.D., is the chemistry lead of the Therapeutics for Rare and Neglected Diseases program within the Division of Pre-Clinical Innovation. Learn more about these and other NCATS staff members via NCATS’ Staff Profiles. Read more >

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NCATS Director Austin delivers keynote address at WORLDSymposium™ 2016, a meeting focused on lysosomal diseases research.


NCATS Director Austin is keynote speaker at RE(ACT) Congress – International Congress on Research of Rare and Orphan Diseases.

Research Opportunities and Announcements Highlight

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