Dear Mr/Mrs <<Last Name>>,
A study has recently been done on the EVRF radiofrequency treatment using the CR45i catheter by Doctor Atilla Szabo in Budapest, Hungary. Findings conclude that treatment with the CR45i catheter results in the desirable outcome of irreversible destruction of the vein wall.
The study consisted of taking histology samples after the treatment of two sheep leg veins to examine the effects of the radiofrequency treatment. The samples were fixed in formaldehyd solution and were examined under microscope after HE staining. 200x and 600x magnification was used.
The treated veins were compared to untreated veins and a clear difference could be seen. Untreated veins showed a normal endothelial layer, an intact media layer and a normal structure of muscle cells and elastic fibres, whereas treated veins clearly showed a desintegrated endothelium layer as a result of the radiofrequency treatment. Furthermore, adherent thrombus was formed in the lumen and the media of treated veins showed damage to the muscle cells and elastic fibres due to the thermal damage caused by the RF treatment with the EVRF CR45i catheter.
The histology samples can be viewed here.