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See below for a daily digest of the latest Huntington's Disease news!

Fungicides Might Contribute to Neurodegenerative Disease Development in Disease Like Huntington’s

Apr 01, 2016 07:00 am | Magdalena Kegel

 

Fungicides disrupt gene expression, possibly increasing the risk of neurodegenerative disease.Researchers discovered that frequently used fungicides – chemicals used commercially to get rid of fungi in crops – cause the same kind of changes in gene expression as scientists report are present in patients with neurodegenerative diseases, such as Huntington’s and Alzheimer’s diseases, as well as autism. The study, “Identification of chemicals that mimic transcriptional changes […]

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Gene Therapy Approach Reported to Block Mutant Huntington’s Gene in Preclinical Studies

Mar 30, 2016 07:00 am | Malika Ammam, PhD

 

Huntington’s disease research grantuniQure recently published results from preclinical studies of its gene therapy program, AMT-130, indicating that a one-time administration of AAV5-delivered therapy into the central nervous system can block the mutant HTT gene that causes Huntington’s disease (HD). These findings, in the article “Design, Characterization, and Lead Selection of Therapeutic miRNAs Targeting Huntingtin for Development of Gene Therapy for […]

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Recent Posts

Huntington’s Education Day Event Set for April 2 at University of North Carolina, Greensboro
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In Huntington’s Disease, Calcium Overload Leads to Mitochondrial Dysfunction and Cell Death
Huntington’s Pathology Seen in Songbirds’ Neuronal and Behavioral Response to HTT Mutation

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