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See below for a daily digest of the latest Parkinson's Disease news & perspectives!

Life’s History Can Lead to a Strong Conductor

Sep 25, 2020 09:00 am | Dr. C

 

hallucinations, stormThe conductor is a mental construct that supports metacognitive processes while in a rested state. That means it is a nonjudgmental observer of the mind that is curious without causing harm. There are many benefits to having a strong conductor, but for me, the most beneficial is the “mind palace.” I use the “mind palace” […]

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Scientists Develop New System to Better Manage Medication Delivery

Sep 25, 2020 07:00 am | Diana Campelo Delgado

 

new delivery systemScientists have developed a new system that can provide a controlled and sustained release of parkinsonian medications, thus enabling better management of Parkinson’s disease. The mechanisms behind this delivery system were described in the study, “Multi-Drug-Loaded Microcapsules with Controlled Release for Management of Parkinson’s Disease,” published in the journal Small. Parkinson’s is characterized by the […]

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Seelos Therapeutics, Duke University Agree to Test SLS-004 in Parkinson’s Pre-Clinical Study

Sep 25, 2020 07:00 am | Forest Ray, PhD

 

SLS-004Seelos Therapeutics has signed an agreement with Duke University in North Carolina to conduct a pre-clinical study of SLS-004, one of its gene therapy candidates, as a treatment for Parkinson’s disease. The proof-of-concept study will seek to determine if the investigational therapy can prevent or delay Parkinson’s disease and also test its safety and effectiveness. If warranted, […]

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Simvastatin Fails to Slow Parkinson’s Progression, Trial Data Shows

Sep 24, 2020 07:00 am | Joana Carvalho, PhD

 

simvastatinSimvastatin, a widely-used cholesterol-lowering medication, failed to slow the progression of Parkinson’s disease, according to data from a Phase 2 trial. Based on these findings, it was decided that a future Phase 3 study assessing the safety and efficacy of simvastatin in these patients would not be justified. Data from the study, called PD-STAT (NCT02787590), […]

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$7.2M Grant Advances Work Into LRRK2 Protein’s Role in Parkinson’s

Sep 24, 2020 07:00 am | Diana Campelo Delgado

 

LRRK2 and diseaseThe Aligning Science Across Parkinson’s (ASAP) initiative has awarded a $7.2 million grant to a research team working to unravel the structure and biology of leucine-rich repeat kinase 2 (LRRK2), a protein linked to familial Parkinson’s disease. The three-year grant, issued by the Michael J. Fox Foundation (MJFF), was given to an international team led by researchers at […]

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