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See below for a daily digest of the latest Parkinson's Disease news & perspectives!

Electrodes Placed in Brain May Offer Way of ‘Sensing’ Parkinson’s Arrival

Sep 16, 2020 07:00 am | Diana Campelo Delgado

 

dopamine and brain tissueEngineers with Michigan State University (MSU) are developing diamond-based electrodes that might detect early warning signs of neurodegenerative diseases such as Parkinson’s in a living brain. MSU researchers Wen Li and Erin Purcell have received $3.4 million in funding from the National Institutes of Health and an MSU Strategic Partnership Grant to conduct preclinical work evaluating the safety, durability, […]

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Supernus Submits SPN-830 Apomorphine Infusion Pump for FDA Approval

Sep 16, 2020 07:00 am | Marisa Wexler

 

SPN-830Supernus Pharmaceuticals has submitted a new drug application to the U.S. Food and Drug Administration (FDA) seeking approval of SPN-830, its apomorphine infusion pump, the company said. If approved, the pump will be used for the continuous treatment of on-off episodes in adults with Parkinson’s disease who continue to experience motor symptoms after treatment with oral levodopa and […]

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Kynmobi Safe, Effective for ‘Off’ Periods Over Long Term, Ongoing Trial Reports

Sep 15, 2020 07:00 am | Marisa Wexler

 

Kynmobi trial dataSunovion‘s Kynmobi (apomorphine hydrochloride), a sublingual film treatment for “off” episodes in people with Parkinson’s disease, has a manageable safety profile and maintains efficacy over up to nearly a year of use, interim data from an ongoing Phase 3 trial show. Findings were presented at MDS Virtual Congress 2020 in the study, “A Long-Term Safety, Tolerability, […]

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Research Shows How PARK7 Gene Mutations Cause Early Onset Parkinson’s

Sep 15, 2020 07:00 am | Steve Bryson PhD

 

PARK7 geneMutations in the PARK7 gene, known to cause early onset Parkinson’s disease, result in low levels of a protein called DJ-1 that is essential for nerve cell health, a study revealed. In fixing a protein processing malfunction in cells derived from members of a single family who carried a particular mutation in this gene, a team […]

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4th-generation DBS System, Vercise Genus, Available in Europe

Sep 14, 2020 07:00 am | Marisa Wexler

 

deep brain stimulationVercise Genus, a fourth-generation system for deep brain stimulation (DBS) made by Boston Scientific, has received CE marking and is now commercially available in Europe. A treatment approach for Parkinson’s disease, DBS involves surgically implanting a neurostimulator to deliver electrical impulses to targeted regions of the brain that control movement, pain, mood, and the like. […]

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Disturbed Sleep Tied to Cognitive Problems in Parkinson’s Patients

Sep 14, 2020 07:00 am | Ines Martins, PhD

 

sleep qualityDisturbed sleep, like that due to sleep apnea, significantly associates with poorer cognition in Parkinson’s disease patients, particularly in the domains of attention, executive function, and memory, a study reported. The study, “Sleep Disturbances and Sleep Disordered Breathing Impair Cognitive Performance in Parkinson’s Disease,” was published in the journal Frontiers in Neuroscience. In addition to […]

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Preventing Conductor Malfunction During a ‘Perfect Storm’

Sep 11, 2020 09:00 am | Dr. C

 

hallucinations, stormIt was one of those “perfect storm” weeks, when everything came together in a cumulative effect to make life miserable. Too much stress on my system makes it exceedingly difficult to use the conductor due to malfunctions. This only happens to me a few times a year, but it is disabling when it does. The […]

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Hidrox, an Olive Extract, Eased Parkinson’s Symptoms in Mice, Study Finds

Sep 11, 2020 07:00 am | Ines Martins, PhD

 

Hidrox studiedHidrox, a compound extracted from olives, can significantly ease Parkinson’s motor symptoms, reduce alpha synuclein buildup, and slow neurodegeneration in animal models of the disease, a recent study has found. Though Hidrox is known mostly for its antioxidant effects, its benefits in Parkinson’s went beyond a decline in oxidative stress; brain inflammation, inflammasome signaling, and […]

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Newly Launched Valted Seq Working to Discover Disease Pathways, Biomarkers

Sep 11, 2020 07:00 am | Forest Ray, PhD

 

biomarkers, Valted SeqD&D Pharmatech has launched a new company called Valted Seq, aimed at discovering pathways and biomarkers relevant to neurodegenerative diseases such as Parkinson’s. To this end, the company claims in a press release to have created the world’s largest repository of single-cell sequencing data. This data comes from high-quality, clinically characterized brain tissues of patients […]

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What the ‘Sandwich Generation’ Tells Us About Heroes

Sep 10, 2020 03:00 pm | Sherri Woodbridge

 

generation, water, care, healthy, chanceI heard something recently that was new to me — that we are living in “sandwich times.” In other words, this is the “sandwich generation.” It’s a time in history when many are simultaneously caring for both a child at home and a parent. Caring for a so-called normal child or adult can be difficult […]

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