Computational Model Explains How Huntington’s Protective Molecular Path Dead-Ends
Nov 01, 2016 03:17 pm | Magdalena Kegel
By using computational modeling, researchers have demonstrated that at the early stages of mutant huntingtin (mHtt) aggregation, a molecular feedback loop works to prevent the effects of the toxic aggregates, until a tipping point is reached. Because the study, “Systemic study of a natural feedback loop in Huntington’s disease at the onset of neurodegeneration,” published […]
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