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See below for a daily digest of the latest Huntington's Disease news!

Critical Path Institute, CHDI Foundation Join Forces to Expedite Huntington’s Therapies

Nov 03, 2016 09:19 am | Carolina Henriques

 

ConsortiumCritical Path Institute (C-Path) and CHDI Foundation have joined forces to create a consortium geared toward clearly defining regulatory pathways for faster approval of new Huntington’s disease (HD) treatments. The new HD Regulatory Science Consortium (HD-RSC) will gather participants from the Huntington’s disease community to expedite regulatory endorsement and to facilitate clinical data standardization and collaboration. Drug development tools, […]

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Computational Model Explains How Huntington’s Protective Molecular Path Dead-Ends

Nov 01, 2016 03:17 pm | Magdalena Kegel

 

A computational model explained how a molecular pathway, protecting cells from the damaging actions of mutant Huntingtin, eventually fails.By using computational modeling, researchers have demonstrated that at the early stages of mutant huntingtin (mHtt) aggregation, a molecular feedback loop works to prevent the effects of the toxic aggregates, until a tipping point is reached. Because the study, “Systemic study of a natural feedback loop in Huntington’s disease at the onset of neurodegeneration,” published […]

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