Huntington’s Disease Therapies May Target Cholesterol Metabolism in Future
Mar 04, 2016 07:00 am | Teresa Pais, PhD
Huntington’s disease (HD) patients are known to have a dysregulation of cholesterol metabolism. Now, researchers have shown that manipulation of cholesterol levels in striatal neurons can improve motor deficits in an animal model of Huntington’s. The study, “CYP46A1, the rate-limiting enzyme for cholesterol degradation, is neuroprotective in Huntington’s disease,” was published in the journal Brain. Huntington’s […]
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