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See below for a daily digest of the latest Huntington's Disease news!

Protein’s Misconduct in Mitochondria May Be Cause of Nerve Cell Death in Huntington’s

Aug 05, 2016 07:00 am | Ines Martins, PhD

 

neurodegenerationStopping the protein TDP-43 from accumulating in mitochondria may help prevent neurodegeneration in a variety of diseases, according to researchers at the Case Western Reserve University. In a recent study, they demonstrated that once inside mitochondria, TDP-43 shuts down its ability to produce energy, leading to nerve cell death. The study, “The inhibition of TDP-43 mitochondrial localization blocks its neuronal […]

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Vaccinex’s VX15 Antibody for Huntington’s Fast Tracked by FDA

Aug 03, 2016 07:00 am | Carolina Henriques

 

VX15 for Huntington'sVaccinex‘s VX15, a novel clinical stage monoclonal antibody for Huntington’s disease (HD) treatment, has been granted Fast Track designation by the U.S. Food and Drug Administration (FDA). VX15 blocks the activity of semaphorin 4D (SEMA4D), a molecule that is thought to promote chronic inflammatory responses in the brain. “We are very pleased that the FDA has granted this important […]

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