Protein’s Misconduct in Mitochondria May Be Cause of Nerve Cell Death in Huntington’s
Aug 05, 2016 07:00 am | Ines Martins, PhD
Stopping the protein TDP-43 from accumulating in mitochondria may help prevent neurodegeneration in a variety of diseases, according to researchers at the Case Western Reserve University. In a recent study, they demonstrated that once inside mitochondria, TDP-43 shuts down its ability to produce energy, leading to nerve cell death. The study, “The inhibition of TDP-43 mitochondrial localization blocks its neuronal […]
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