Donor Group Updates
nPOD had some really important cases in the first quarter of 2015, including:
Please be sure to check our Donor Summary Table and Aperio Online Pathology periodically to see what is new to aid your research.
- 6325 that had 6 years T1D with significant insulitis
- 6324 that had T1D for less than two years (GADA+ and HbA1C 10.2)
- 6323 islet pilot case 5 years disease duration
- 6314 autoantibody positive case
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New Projects and Publications
New Investigators: We want to welcome the following new investigators to the nPOD consortium:
If you know other investigators that would like to become part of our project, we encourage them to Apply to Join nPOD.
- Reza Abdi with JinJun Cheng--Use of T1D pancreatic and lymphoid tissue to assess the expression of adhesion molecules
- Anil Bhushan with Mark Atkinson, Todd Brusko and Bita Bordbar--Epigeneic analysis on nPOD islet cells
- Susan Bonner-Weir with Anmar Khadra--Origin composite islet structure in human
- Barbara Coulson --Analysis of type 1 interferon to responses to rotavirus in patients with type 1 diabetes
- Irina Kusmartseva with Alberto Pugliese--Assay validation and generation of preliminary data (retired cases)
- Etienne Larger with Marc Diedisheim and Roberto Mallone--Beta-cell mass in Antibody-positive non-diabetic subjects
- Kathrin Maedler with Federico Paroni--Detection of coxsackievirus infection in Beta cells in T1D by short fluorescently labeled oligonucleotide probes
- Peter Thorn--Beta cell polarity
Reminder: If you have a publication that relies on nPOD tissues, we want to know about it!
Please fill out the Abstract & Submission form on the nPOD website.
New publications: Congratulations to our investigators for the following publications over the last few months.
Battaglia M, Atkinson M. (2015) The Streetlight Effect in Type 1 Diabetes. Diabetes. 2015 Apr;64(4):1081-90. doi: 10.2337/db14-1208.
Reddy S, Zeng N, Al-Diery H, Jung D, Yeu C, Joret MO, Merrilees MJ, Wu F. (2015) Analysis of peri-islet CD45-positive leucocytic infiltrates in long-standing type 1 diabetic patients. Diabetologia. 2015 Feb 17. [Epub ahead of print]
Staff Changes at nPOD
Irina Kusmartseva: We are pleased to announce that Dr. Irina Kusmartseva has been appointed as nPOD Organ Procurement and Processing Center (OPPC) Director. Dr. Kusmartseva is an immunologist by training with over 14 years of research experience. Prior to joining JDRF nPOD, Dr. Kusmartseva worked at Duke University Medical Center, H. Lee Moffitt Cancer Center and Mount Sinai Medical School. Irina is no stranger for nPOD investigators and has been relentlessly helping our investigators select proper donor cases and samples for a wide variety projects. Irina has been working at nPOD as OPPC lab manager for the past 4 years and we are very happy today that she is taking the leading role as OPPC Director.
Tiffany Philips: Tiffany is a Senior Biological Scientist that has been part of our Organ Processing and Pathology Core (OPPC) for since October of 2011. She has been involved in over 150 cases and often volunteers her time to assist with cases even when she's not on call. She is leaving nPOD this summer to pursue her degree as a Pathology Assistant at the University of Maryland. We wish her the best of luck in all her future endeavors!
Farewell from Jayne Moraski: As I write my last newsletter for nPOD, I want to thank all of our recovery partners for working with me. It has truly been my pleasure to be a part of your amazing programs. As of June 1st, I will be heading back to my roots in housing and community development, to become the Executive Director of the Family Promise of Gainesville--a program that helps homeless children and their families find housing and self-sufficiency.
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